Cold stress and cholinergic supersensitivity
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منابع مشابه
Cold stress and cholinergic supersensitivity.
To the Editor: In the rat (adult male Sprague-Dawley) chronic forced swim stress (Dilsaver et al. 1986) and chronic inescapable footshock (Dilsaver and Alessi 1987) induce marked supersensitivity to the hypothermic effects of the muscarinic cholinergic agonist oxotremorine. These observations are consistent with a report that immobilization of 10 min duration activates the septohippocampal musc...
متن کاملStress induces supersensitivity of a cholinergic system in rats.
Cholinergic system supersensitivity may be involved in the pathophysiology of depressive disorders (Janowsky et al. 1972; Dilsaver and Greden 1984; Dilsaver 1986). Associations between stressful events and onset of depressive (Lloyd 1980) and manic (Kennedy et al. 1983) episodes are documented. Janowsky et al. (1983) proposed that stress increases the sensitivity of central cholinergic mechanis...
متن کاملChronic inescapable footshock produces cholinergic system supersensitivity.
Webb W, Campbell SS (1983): Relationships in sleep characteristics of identical and fraternal twins. Arch Gen Psychiatry 40: 10931095. Weissman MM, Gershon ES, Kidd KK, Prusoff BA, Leckman JF, Dibble E, Hamovit J, Thompson D, Pauls DL, Guroff JJ (1984): Psychiatric disorders in the relatives of probands with affective disorders. The Yale University-National Institute of Mental Health Collaborat...
متن کاملDissociation of cholinergic supersensitivity from receptor number in ciliary muscle.
Ciliary ganglionectomy in the cynomolgus monkey produced loss of the accommodative response to electrical stimulation of the Edinger-Westphal nucleus and to topical eserine, concurrent with enhanced responsiveness to topical and systemic pilocarpine. This supersensitivity produced by parasympathetic denervation was not associated with an increase in muscarinic receptor number or affinity measur...
متن کاملCold stress and the cold pressor test.
Temperature and other environmental stressors are known to affect blood pressure and heart rate. In this activity, students perform the cold pressor test, demonstrating increased blood pressure during a 1- to 2-min immersion of one hand in ice water. The cold pressor test is used clinically to evaluate autonomic and left ventricular function. This activity is easily adapted to an inquiry format...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 1987
ISSN: 0006-3223
DOI: 10.1016/0006-3223(87)90023-0